Sunday 24 May 2015

What is Cushing's Syndrome?

Cushing's syndrome is a disorder that occurs when the body has a high level of the hormone cortisol.

The causes of this syndrome are:
  1. Medication containing a cortisol-like synthetic compound called glucocorticoid
  2. A benign or malignant tumor in the body that makes the adrenal gland produce too much cortisol. (Much less common cause then medicine.)
  • Pituitary adenoma is a benign pituitary tumor that secretes ACTH. Most common tumor linked to Cushing’s syndrome => So common that it’s been given it’s own term, Cushing’s disease.

  • Adrenal tumors produce cortisol in their tissue, adding to the amount already produced by the adrenal glands (cause about 15% of endogenous Cushing’s syndrome cases). More common in children and less common in adults.
  • Some tumors not in the pituitary or adrenal glands can produce ACTH and force more cortisol production.



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